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Plexin B1 suppresses c-Met in melanoma: a role for Plexin B1 as a tumor suppressor protein through regulation of c-Met

Melanoma arises through complex genetic and epigenetic changes resulting in uncontrolled proliferation, invasion and metastatic disease. Semaphorins are critical regulators of axon guidance through interaction with their receptors, Plexins and neuropilins. Aberrant expression of Plexin receptors is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stevens, Laurel, McClelland, Lindy, Fricke, Alex, Williamson, Magali, Scott, Glynis
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3657133/
https://ncbi.nlm.nih.gov/pubmed/20164843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2010.13
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