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Solvation in protein folding analysis: Combination of theoretical and experimental approaches

An effort to combine theoretical analyses and protein engineering methods has been made to probe the folding mechanism of SH3 by using Energy Landscape Theory and a φ-value analysis. Particular emphasis was given to core residues and the effect of desolvation during the folding event by replacing th...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Fernández-Escamilla, A. M., Cheung, M. S., Vega, M. C., Wilmanns, M., Onuchic, J. N., Serrano, L.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304180101
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