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Solvation in protein folding analysis: Combination of theoretical and experimental approaches

An effort to combine theoretical analyses and protein engineering methods has been made to probe the folding mechanism of SH3 by using Energy Landscape Theory and a φ-value analysis. Particular emphasis was given to core residues and the effect of desolvation during the folding event by replacing th...

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Detalhes bibliográficos
Main Authors: Fernández-Escamilla, A. M., Cheung, M. S., Vega, M. C., Wilmanns, M., Onuchic, J. N., Serrano, L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC365706/
https://ncbi.nlm.nih.gov/pubmed/14978284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0304180101
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