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Solvation in protein folding analysis: Combination of theoretical and experimental approaches

An effort to combine theoretical analyses and protein engineering methods has been made to probe the folding mechanism of SH3 by using Energy Landscape Theory and a φ-value analysis. Particular emphasis was given to core residues and the effect of desolvation during the folding event by replacing th...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Fernández-Escamilla, A. M., Cheung, M. S., Vega, M. C., Wilmanns, M., Onuchic, J. N., Serrano, L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2004
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365706/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14978284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304180101
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