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The nonconserved wrapping of conserved protein folds reveals a trend toward increasing connectivity in proteomic networks

Although protein folding domains are generally conserved for function across distant homologous sequences, one crucial structural feature is not conserved: the wrapping of backbone hydrogen bonds, that is, the extent to which they are intramolecularly desolvated and thereby protected from water atta...

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Autors principals: Fernández, Ariel, Scott, Ridgway, Berry, R. Stephen
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC365704/
https://ncbi.nlm.nih.gov/pubmed/14978274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308295100
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