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Glutamate-183 in the conserved TGES motif of domain A of sarcoplasmic reticulum Ca(2+)-ATPase assists in catalysis of E(2)/E(2)P partial reactions

The recently determined crystal structures of the sarcoplasmic reticulum Ca(2+)-ATPase show that in the E(1)Ca(2) form, domain A is almost isolated from the other cytoplasmic domains, P and N, whereas in E(2), domain A has approached domains P and N, with E183 of the highly conserved P-type ATPase s...

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Autores principales: Clausen, Johannes D., Vilsen, Bente, McIntosh, David B., Einholm, Anja P., Andersen, Jens Peter
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC365696/
https://ncbi.nlm.nih.gov/pubmed/14970331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0400122101
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