Structural basis of tyrosine sulfation and V(H)-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120

The conserved surface of the HIV-1 gp120 envelope glycoprotein that binds to the HIV-1 coreceptor is protected from humoral recognition by multiple layers of camouflage. Here we present sequence and genomic analyses for 12 antibodies that pierce these defenses and determine the crystal structures of...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Huang, Chih-chin, Venturi, Miro, Majeed, Shahzad, Moore, Michael J., Phogat, Sanjay, Zhang, Mei-Yun, Dimitrov, Dimiter S., Hendrickson, Wayne A., Robinson, James, Sodroski, Joseph, Wyatt, Richard, Choe, Hyeryun, Farzan, Michael, Kwong, Peter D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14981267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0308527100
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia