Combined Anti-Inflammatory and Anti-AGE Drug Treatments Have a Protective Effect on Intervertebral Discs in Mice with Diabetes

OBJECTIVE: Diabetes and low back pain are debilitating diseases and modern epidemics. Diabetes and obesity are also highly correlated with intervertebral disc (IVD) degeneration and back pain. Advanced-glycation-end-products (AGEs) increase reactive-oxygen-species (ROS) and inflammation, and are one...

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Detalhes bibliográficos
Main Authors: Illien-Junger, Svenja, Grosjean, Fabrizio, Laudier, Damien M., Vlassara, Helen, Striker, Gary E., Iatridis, James C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656842/
https://ncbi.nlm.nih.gov/pubmed/23691192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0064302
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