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Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention

SIGNIFICANCE: Myofibroblasts are responsible for wound closure that occurs in healed acute wounds. However, their actions can result in disfiguring scar contractures, compromised organ function, and a tumor promoting stroma. Understanding the mechanisms regulating their contractile machinery, gene e...

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Bibliografische gegevens
Hoofdauteurs: Van De Water, Livingston, Varney, Scott, Tomasek, James J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2013
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656629/
https://ncbi.nlm.nih.gov/pubmed/24527336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/wound.2012.0393
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