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The first and fourth upstream open reading frames in GCN4 mRNA have similar initiation efficiencies but respond differently in translational control to change in length and sequence.

The third and fourth AUG codons in GCN4 mRNA efficiently repress translation of the GCN4-coding sequences under normal growth conditions. The first AUG codon is approximately 30-fold less inhibitory and is required under amino acid starvation conditions to override the repressing effects of AUG codo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Mueller, P P, Jackson, B M, Miller, P F, Hinnebusch, A G
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1988
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3072481/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5439-5447.1988
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