Host-derived CD8(+) dendritic cells are required for induction of optimal graft-versus-tumor responses after experimental allogeneic bone marrow transplantation

The graft-versus-tumor (GVT) effect after allogeneic hematopoietic cell transplantation (allo-HCT) represents an effective form of immunotherapy against many malignancies. Meaningful separation of the potentially curative GVT responses from graft-versus-host disease (GVHD), the most serious toxicity...

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Autori principali: Toubai, Tomomi, Sun, Yaping, Luker, Gary, Liu, Jun, Luker, Kathryn E., Tawara, Isao, Evers, Rebecca, Liu, Chen, Mathewson, Nathan, Malter, Chelsea, Nieves, Evelyn, Choi, Sung, Murphy, Kenneth M., Reddy, Pavan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2013
Soggetti:
Transplantation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656455/
https://ncbi.nlm.nih.gov/pubmed/23520337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-432872
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