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Matrix attachment regions are positioned near replication initiation sites, genes, and an interamplicon junction in the amplified dihydrofolate reductase domain of Chinese hamster ovary cells.

Genomic DNA in higher eucaryotic cells is organized into a series of loops, each of which may be affixed at its base to the nuclear matrix via a specific matrix attachment region (MAR). In this report, we describe the distribution of MARs within the amplified dihydrofolate reductase (DHFR) domain (a...

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Библиографические подробности
Опубликовано в::Mol Cell Biol
Главные авторы: Dijkwel, P A, Hamlin, J L
Формат: Artigo
Язык:Inglês
Опубликовано: Taylor & Francis 1988
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Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365642/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3244360/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5398-5409.1988
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