Molecular Mechanisms of the Cytotoxicity of Human α-Lactalbumin Made Lethal to Tumor Cells (HAMLET) and Other Protein-Oleic Acid Complexes

Although HAMLET (human α-lactalbumin made lethal to tumor cells), a complex formed by human α-lactalbumin and oleic acid, has a unique apoptotic activity for the selective killing of tumor cells, the molecular mechanisms of expression of the HAMLET activity are not well understood. Therefore, we stu...

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Main Authors: Nakamura, Takashi, Aizawa, Tomoyasu, Kariya, Ryusho, Okada, Seiji, Demura, Makoto, Kawano, Keiichi, Makabe, Koki, Kuwajima, Kunihiro
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656296/
https://ncbi.nlm.nih.gov/pubmed/23580643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.437889
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