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Inhibition of Isoleucyl-tRNA Synthetase as a Potential Treatment for Human African Trypanosomiasis

Trypanosoma brucei sp. causes human African trypanosomiasis (HAT; African sleeping sickness). The parasites initially proliferate in the hemolymphatic system and then invade the central nervous system, which is lethal if not treated. New drugs are needed for HAT because the approved drugs are few, t...

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Bibliografski detalji
Glavni autori: Cestari, Igor, Stuart, Kenneth
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656282/
https://ncbi.nlm.nih.gov/pubmed/23548908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447441
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