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Inhibition of Isoleucyl-tRNA Synthetase as a Potential Treatment for Human African Trypanosomiasis

Trypanosoma brucei sp. causes human African trypanosomiasis (HAT; African sleeping sickness). The parasites initially proliferate in the hemolymphatic system and then invade the central nervous system, which is lethal if not treated. New drugs are needed for HAT because the approved drugs are few, t...

詳細記述

保存先:
書誌詳細
主要な著者: Cestari, Igor, Stuart, Kenneth
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656282/
https://ncbi.nlm.nih.gov/pubmed/23548908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.447441
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