Each Individual Isoform of the Dopamine D2 Receptor Protects from Lactotroph Hyperplasia

Dopamine acting through D2 receptors (D2Rs) controls lactotroph proliferation and prolactin (PRL) levels. Ablation of this receptor in mice results in lactotroph hyperplasia and prolactinomas in aged females. Alternative splicing of the Drd2 gene generates 2 independent isoforms, a long (D2L) and a...

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Bibliografische gegevens
Hoofdauteurs: Radl, Daniela, De Mei, Claudia, Chen, Eric, Lee, Hyuna, Borrelli, Emiliana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2013
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656237/
https://ncbi.nlm.nih.gov/pubmed/23608643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1008
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