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Each Individual Isoform of the Dopamine D2 Receptor Protects from Lactotroph Hyperplasia
Dopamine acting through D2 receptors (D2Rs) controls lactotroph proliferation and prolactin (PRL) levels. Ablation of this receptor in mice results in lactotroph hyperplasia and prolactinomas in aged females. Alternative splicing of the Drd2 gene generates 2 independent isoforms, a long (D2L) and a...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3656237/ https://ncbi.nlm.nih.gov/pubmed/23608643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1008 |
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