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Dopamine D2 receptors in striatal output neurons enable the psychomotor effects of cocaine

The psychomotor effects of cocaine are mediated by dopamine (DA) through stimulation of striatal circuits. Gabaergic striatal medium spiny neurons (MSNs) are the only output of this pivotal structure in the control of movements. The majority of MSNs express either the DA D1 or D2 receptors (D1R, D2R...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Kharkwal, Geetika, Radl, Daniela, Lewis, Robert, Borrelli, Emiliana
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5068268/
https://ncbi.nlm.nih.gov/pubmed/27671625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608362113
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