Interaction of a hepatoma-specific nuclear factor with transcription-regulatory sequences of the human alpha-fetoprotein and albumin genes.

DNase I footprinting and gel mobility shift analysis showed that an HuH-7 hepatoma nuclear protein, termed AFP1, binds specifically to an AT-rich sequence, TGATTAATAATTACA, in domain B of the human alpha-fetoprotein enhancer. No such binding activity was found in HeLa cell nuclei. Transient transfec...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Sawadaishi, K, Morinaga, T, Tamaoki, T
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1988
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365620/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2468995/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5179-5187.1988
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