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Mitochondrial import and processing of mutant human ornithine transcarbamylase precursors in cultured cells.

We have investigated mitochondrial import and processing of the precursor for human ornithine transcarbamylase (OTC; carbamoylphosphate:L-ornithine carbamoyltransferase, EC 2.1.3.3) in HeLa cells stably transformed with cDNA sequences encoding OTC precursors carrying mutations in their leader peptid...

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Udgivet i:Mol Cell Biol
Principais autores: Isaya, G, Fenton, W A, Hendrick, J P, Furtak, K, Kalousek, F, Rosenberg, L E
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1988
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3244350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.12.5150-5158.1988
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