IL-21 Restricts Virus-driven Treg Cell Expansion in Chronic LCMV Infection

Foxp3(+) regulatory T (Treg) cells are essential for the maintenance of immune homeostasis and tolerance. During viral infections, Treg cells can limit the immunopathology resulting from excessive inflammation, yet potentially inhibit effective antiviral T cell responses and promote virus persistenc...

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Detalhes bibliográficos
Main Authors: Schmitz, Iwana, Schneider, Christoph, Fröhlich, Anja, Frebel, Helge, Christ, Daniel, Leonard, Warren J., Sparwasser, Tim, Oxenius, Annette, Freigang, Stefan, Kopf, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3656089/
https://ncbi.nlm.nih.gov/pubmed/23696736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003362
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