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Exhausted CD8(+) T cells exhibit low and strongly inhibited TCR signaling during chronic LCMV infection
Chronic viral infections are often associated with impaired CD8(+) T cell function, referred to as exhaustion. Although the molecular and cellular circuits involved in CD8(+) T cell exhaustion are well defined, with sustained presence of antigen being one important parameter, how much T cell recepto...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7479152/ https://ncbi.nlm.nih.gov/pubmed/32901001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18256-4 |
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