Monoallelic Chromatin Conformation Flanking Long-Range Silenced Domains in Cancer-Derived and Normal Cells

Epigenetic inactivation of chromatin plays an important role in determining cell phenotype in both normal and cancer cells, but our knowledge is still incomplete with respect to any potential monoallelic nature of the phenomenon. We have genotyped DNA isolated from chromatin of two colorectal cancer...

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Bibliographische Detailangaben
Hauptverfasser: Di Paola, Domenic, Raelson, John, Rampakakis, Emmanouil, Basik, Mark, Zannis-Hadjopoulos, Maria, Bradley, W. Edward C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655995/
https://ncbi.nlm.nih.gov/pubmed/23696799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063190
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