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A short carboxyl-terminal tail is required for single-stranded DNA binding, higher-order structural organization, and stability of the mitochondrial single-stranded annealing protein Mgm101
Mgm101 is a Rad52-type single-stranded annealing protein (SSAP) required for mitochondrial DNA (mtDNA) repair and maintenance. Structurally, Mgm101 forms large oligomeric rings. Here we determine the function(s) of a 32–amino acid carboxyl-terminal tail (Mgm101(238–269)) conserved in the Mgm101 fami...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The American Society for Cell Biology
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655812/ https://ncbi.nlm.nih.gov/pubmed/23536705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-01-0006 |
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