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A Properly Configured Ring Structure Is Critical for the Function of the Mitochondrial DNA Recombination Protein, Mgm101

Mgm101 is a Rad52-type recombination protein of bacteriophage origin required for the repair and maintenance of mitochondrial DNA (mtDNA). It forms large oligomeric rings of ∼14-fold symmetry that catalyze the annealing of single-stranded DNAs in vitro. In this study, we investigated the structural...

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Autors principals: Nardozzi, Jonathan D., Wang, Xiaowen, Mbantenkhu, MacMillan, Wilkens, Stephan, Chen, Xin Jie
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3481324/
https://ncbi.nlm.nih.gov/pubmed/22948312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.389965
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