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Inhibitory Effects of Baicalin on the Expression and Activity of CYP3A Induce the Pharmacokinetic Changes of Midazolam in Rats

Baicalin, a flavonoid compound isolated from Scutellaria baicalensis, has been shown to possess antiinflammatory, antiviral, antitumour, and immune regulatory properties. The present study evaluated the potential herb-drug interaction between baicalin and midazolam in rats. Coadministration of a sin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tian, Xin, Cheng, Zhen-Yu, Jin, Han, Gao, Jie, Qiao, Hai-Ling
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655607/
https://ncbi.nlm.nih.gov/pubmed/23710212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/179643
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