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Selective Binding of anti-DNA Antibodies to Native dsDNA Fragments of Differing Sequence

Systemic autoimmune diseases are characterized by the development of autoantibodies directed against a limited subset of nuclear antigens, including DNA. DNA-specific B cells take up mammalian DNA through their B cell receptor, and this DNA is subsequently transported to an endosomal compartment whe...

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Detalhes bibliográficos
Main Authors: Uccellini, Melissa B., Busto, Patricia, Debatis, Michelle, Marshak-Rothstein, Ann, Viglianti, Gregory A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655556/
https://ncbi.nlm.nih.gov/pubmed/22285306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2012.01.003
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