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Selective Binding of anti-DNA Antibodies to Native dsDNA Fragments of Differing Sequence
Systemic autoimmune diseases are characterized by the development of autoantibodies directed against a limited subset of nuclear antigens, including DNA. DNA-specific B cells take up mammalian DNA through their B cell receptor, and this DNA is subsequently transported to an endosomal compartment whe...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655556/ https://ncbi.nlm.nih.gov/pubmed/22285306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.imlet.2012.01.003 |
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