P53-INDEPENDENT, NORMAL STEM CELL SPARING EPIGENETIC-DIFFERENTIATION THERAPY FOR MYELOID AND OTHER MALIGNANCIES

Cytotoxic chemotherapy for acute myeloid leukemia (AML) usually produces only temporary remissions, at the cost of significant toxicity and risk for death. One fundamental reason for treatment failure is that it is designed to activate apoptosis genes (eg., TP53) that may be unavailable because of m...

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Autores principales: Saunthararajah, Yogen, Triozzi, Pierre, Rini, Brian, Singh, Arun, Radivoyevitch, Tomas, Sekeres, Mikkael, Advani, Anjali, Tiu, Ramon, Reu, Frederic, Kalaycio, Matt, Copelan, Ed, Hsi, Eric, Lichtin, Alan, Bolwell, Brian
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655437/
https://ncbi.nlm.nih.gov/pubmed/22289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2011.11.011
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