P53-INDEPENDENT, NORMAL STEM CELL SPARING EPIGENETIC-DIFFERENTIATION THERAPY FOR MYELOID AND OTHER MALIGNANCIES

Cytotoxic chemotherapy for acute myeloid leukemia (AML) usually produces only temporary remissions, at the cost of significant toxicity and risk for death. One fundamental reason for treatment failure is that it is designed to activate apoptosis genes (eg., TP53) that may be unavailable because of m...

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Autori principali: Saunthararajah, Yogen, Triozzi, Pierre, Rini, Brian, Singh, Arun, Radivoyevitch, Tomas, Sekeres, Mikkael, Advani, Anjali, Tiu, Ramon, Reu, Frederic, Kalaycio, Matt, Copelan, Ed, Hsi, Eric, Lichtin, Alan, Bolwell, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655437/
https://ncbi.nlm.nih.gov/pubmed/22289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2011.11.011
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