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P53-INDEPENDENT, NORMAL STEM CELL SPARING EPIGENETIC-DIFFERENTIATION THERAPY FOR MYELOID AND OTHER MALIGNANCIES
Cytotoxic chemotherapy for acute myeloid leukemia (AML) usually produces only temporary remissions, at the cost of significant toxicity and risk for death. One fundamental reason for treatment failure is that it is designed to activate apoptosis genes (eg., TP53) that may be unavailable because of m...
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| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655437/ https://ncbi.nlm.nih.gov/pubmed/22289496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2011.11.011 |
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