P53-INDEPENDENT, NORMAL STEM CELL SPARING EPIGENETIC-DIFFERENTIATION THERAPY FOR MYELOID AND OTHER MALIGNANCIES

Cytotoxic chemotherapy for acute myeloid leukemia (AML) usually produces only temporary remissions, at the cost of significant toxicity and risk for death. One fundamental reason for treatment failure is that it is designed to activate apoptosis genes (eg., TP53) that may be unavailable because of m...

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Bibliografische gegevens
Hoofdauteurs: Saunthararajah, Yogen, Triozzi, Pierre, Rini, Brian, Singh, Arun, Radivoyevitch, Tomas, Sekeres, Mikkael, Advani, Anjali, Tiu, Ramon, Reu, Frederic, Kalaycio, Matt, Copelan, Ed, Hsi, Eric, Lichtin, Alan, Bolwell, Brian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655437/
https://ncbi.nlm.nih.gov/pubmed/22289496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.seminoncol.2011.11.011
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