Genetic and epigenetic mutations affect the DNA binding capability of human ZFP57 in transient neonatal diabetes type 1

In the mouse, ZFP57 contains three classical Cys(2)His(2) zinc finger domains (ZF) and recognizes the methylated TGC(met)CGC target sequence using the first and the second ZFs. In this study, we demonstrate that the human ZFP57 (hZFP57) containing six Cys(2)His(2) ZFs, binds the same methylated sequ...

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Xehetasun bibliografikoak
Egile Nagusiak: Baglivo, Ilaria, Esposito, Sabrina, De Cesare, Lucia, Sparago, Angela, Anvar, Zahra, Riso, Vincenzo, Cammisa, Marco, Fattorusso, Roberto, Grimaldi, Giovanna, Riccio, Andrea, Pedone, Paolo V.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Science B.V 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655262/
https://ncbi.nlm.nih.gov/pubmed/23499433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2013.02.045
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