Short-Term Genome Stability of Serial Clostridium difficile Ribotype 027 Isolates in an Experimental Gut Model and Recurrent Human Disease

BACKGROUND: Clostridium difficile whole genome sequencing has the potential to identify related isolates, even among otherwise indistinguishable strains, but interpretation depends on understanding genomic variation within isolates and individuals. METHODS: Serial isolates from two scenarios were wh...

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Autors principals: Eyre, David W., Walker, A. Sarah, Freeman, Jane, Baines, Simon D., Fawley, Warren N., Chilton, Caroline H., Griffiths, David, Vaughan, Alison, Crook, Derrick W., Peto, Tim E. A., Wilcox, Mark H.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655144/
https://ncbi.nlm.nih.gov/pubmed/23691061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063540
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