Short-Term Genome Stability of Serial Clostridium difficile Ribotype 027 Isolates in an Experimental Gut Model and Recurrent Human Disease

BACKGROUND: Clostridium difficile whole genome sequencing has the potential to identify related isolates, even among otherwise indistinguishable strains, but interpretation depends on understanding genomic variation within isolates and individuals. METHODS: Serial isolates from two scenarios were wh...

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Detalhes bibliográficos
Main Authors: Eyre, David W., Walker, A. Sarah, Freeman, Jane, Baines, Simon D., Fawley, Warren N., Chilton, Caroline H., Griffiths, David, Vaughan, Alison, Crook, Derrick W., Peto, Tim E. A., Wilcox, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3655144/
https://ncbi.nlm.nih.gov/pubmed/23691061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063540
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