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ApoE and TDP-43 neuropathology in two siblings with familial FTLD-motor neuron disease
Frontotemporal lobar degeneration with motor neuron disease (FTLD-MND) is characterized by neuronal cytoplasmic inclusions containing TDP-43. Apolipoprotein E4 (apoE4), derived from the apoE ε4 allele, enhances brain atrophy in FTLD through unknown mechanisms. Here, we studied two siblings with C9OR...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2012
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3655113/ https://ncbi.nlm.nih.gov/pubmed/22512241 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/13554794.2012.667124 |
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