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Formation of an inverted duplication can be an initial step in gene amplification.

We have developed a gene transfer approach to facilitate the identification and isolation of chromosomal regions which are prone to high-frequency gene amplification. Such regions are identified by assaying for transformants which show high-frequency resistance to PALA and/or methotrexate by amplifi...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Ruiz, J C, Wahl, G M
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365503/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3185551/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.8.10.4302
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