Enhanced Ca(2+) transport and muscle relaxation in skeletal muscle from sarcolipin-null mice

Sarcolipin (SLN) inhibits sarco(endo)plasmic reticulum Ca(2+)-ATPase (SERCA) pumps. To evaluate the physiological significance of SLN in skeletal muscle, we compared muscle contractility and SERCA activity between Sln-null and wild-type mice. SLN protein expression in wild-type mice was abundant in...

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Hoofdauteurs: Tupling, A. Russell, Bombardier, Eric, Gupta, Subash C., Hussain, Dawar, Vigna, Chris, Bloemberg, Darin, Quadrilatero, Joe, Trivieri, Maria G., Babu, Gopal J., Backx, Peter H., Periasamy, Muthu, MacLennan, David H., Gramolini, Anthony O.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654932/
https://ncbi.nlm.nih.gov/pubmed/21697544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00409.2010
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