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Integrating peptides' sequence and energy of contact residues information improves prediction of peptide and HLA-I binding with unknown alleles

BACKGROUND: The HLA (human leukocyte antigen) class I is a kind of molecule encoded by a large family of genes and is characteristic of high polymorphism. Now the number of the registered HLA-I molecules has exceeded 3000. Slight differences in the amino acid sequences of HLAs would make them bind t...

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Detalhes bibliográficos
Main Authors: Luo, Fei, Gao, Yangyang, Zhu, Yongqiong, Liu, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654895/
https://ncbi.nlm.nih.gov/pubmed/23815611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-14-S8-S1
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