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Label-Free Protein Quantitation Using Weighted Spectral Counting

Mass spectrometry (MS)-based shotgun proteomics allows protein identifications even in complex biological samples. Protein abundances can then be estimated from the counts of MS/MS spectra attributable to each protein, provided that one corrects for differential MS-detectability of the contributing...

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Bibliographic Details
Main Authors: Vogel, Christine, Marcotte, Edward M.
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654649/
https://ncbi.nlm.nih.gov/pubmed/22665309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-885-6_20
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