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Zinc-Dependent Lysosomal Enlargement in TRPML1-Deficient Cells Involves MTF-1 Transcription Factor and ZnT4 (Slc30a4) Transporter

Zn is critical for a multitude of cellular processes, including gene expression, secretion and enzymatic activities. Cellular Zn is controlled by Zn-chelating proteins and by Zn transporters. The recent identification of Zn permeability of the lysosomal ion channel TRPML1, and the evidence of abnorm...

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Bibliografiset tiedot
Päätekijät: Kukic, Ira, Lee, Jeffrey K., Coblentz, Jessica, Kelleher, Shannon L., Kiselyov, Kirill
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654546/
https://ncbi.nlm.nih.gov/pubmed/23368743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20121506
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