Ca(V)1 and Ca(V)2 Channels Engage Distinct Modes of Ca(2+) Signaling to Control CREB-dependent Gene Expression

Activity-dependent gene expression triggered by Ca(2+) entry into neurons is critical for learning and memory, but whether specific sources of Ca(2+) act distinctly or merely supply Ca(2+) to a common pool remains uncertain. Here we report that both signaling modes co-exist and pertain to Ca(V)1 and...

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Bibliografiska uppgifter
Huvudupphovsmän: Wheeler, Damian G., Groth, Rachel D., Ma, Huan, Barrett, Curtis F., Owen, Scott F., Safa, Parsa, Tsien, Richard W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654514/
https://ncbi.nlm.nih.gov/pubmed/22632974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.03.041
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