CaMKII locally encodes L-type channel activity to signal to nuclear CREB in excitation–transcription coupling

Communication between cell surface proteins and the nucleus is integral to many cellular adaptations. In the case of ion channels in excitable cells, the dynamics of signaling to the nucleus are particularly important because the natural stimulus, surface membrane depolarization, is rapidly pulsatil...

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Hlavní autoři: Wheeler, Damian G., Barrett, Curtis F., Groth, Rachel D., Safa, Parsa, Tsien, Richard W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2008
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592819/
https://ncbi.nlm.nih.gov/pubmed/19047462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805048
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