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Inter-channel scaffolding of presynaptic CaV2.2 via the C terminal PDZ ligand domain

Calcium entry through CaV2.2 calcium channels clustered at the active zone (AZ) of the presynaptic nerve terminal gates synaptic vesicle (SV) fusion and the discharge of neurotransmitters, but the mechanism of channel scaffolding remains poorly understood. Recent studies have implicated the binding...

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Detalhes bibliográficos
Main Authors: Gardezi, Sabiha R., Li, Qi, Stanley, Elise F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654268/
https://ncbi.nlm.nih.gov/pubmed/23789098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20134267
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