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Hunting human disease genes: lessons from the past, challenges for the future
The concept that a specific alteration in an individual’s DNA can result in disease is central to our notion of molecular medicine. The molecular basis of more than 3,500 Mendelian disorders has now been identified. In contrast, the identification of genes for common disease has been much more chall...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer-Verlag
2013
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3654184/ https://ncbi.nlm.nih.gov/pubmed/23504071 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-013-1286-3 |
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