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Chronic central ghrelin infusion reduces blood pressure and heart rate despite increasing appetite and promoting weight gain in normotensive and hypertensive rats

Acute studies showed that ghrelin acts on the central nervous system (CNS) to reduce blood pressure (BP), heart rate (HR) and sympathetic activity. However, the long-term CNS cardiovascular actions of ghrelin are still unclear. We tested whether chronic intracerebroventricular (ICV) infusion of ghre...

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Detalhes bibliográficos
Main Authors: Freeman, John N., do Carmo, Jussara M., Adi, Ahmad H., da Silva, Alexandre A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3654065/
https://ncbi.nlm.nih.gov/pubmed/23416021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.peptides.2013.02.003
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