Control of appetite, blood glucose, and blood pressure during melanocortin-4 receptor activation in normoglycemic and diabetic NPY-deficient mice

Although central melanocortin 4 receptor (MC4R) blockade abolishes the central nervous system (CNS)-mediated anorexogenic, antidiabetic, and cardiovascular actions of leptin, chronic MC4R stimulation fails to completely mimic the effects of leptin. Because neuropeptide Y (NPY) and MC4R exert opposit...

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Detaylı Bibliyografya
Yayımlandı:Am J Physiol Regul Integr Comp Physiol
Asıl Yazarlar: da Silva, Alexandre A., Freeman, J. Nathan, Hall, John E., do Carmo, Jussara M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2018
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5966815/
https://ncbi.nlm.nih.gov/pubmed/29351428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00293.2017
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