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Negative regulation contributes to tissue specificity of the immunoglobulin heavy-chain enhancer.

We have identified in and around the immunoglobulin heavy-chain enhancer two apparently distinct negative regulatory elements which repress immunoglobulin H enhancer, simian virus 40 enhancer, and heterologous promoter activity in fibroblasts but not in myeloma cells. We propose that in nonlymphoid...

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Udgivet i:Mol Cell Biol
Principais autores: Imler, J L, Lemaire, C, Wasylyk, C, Wasylyk, B
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365391/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3039350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.7.2558-2567.1987
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