The C-Terminus of Human Nucleotide Receptor P2X7 Is Critical for Receptor Oligomerization and N-Linked Glycosylation

BACKGROUND: The P2X(7) receptor binds extracellular ATP to mediate numerous inflammatory responses and is considered a potential biomarker and therapeutic target for diverse inflammatory and neurological diseases. P2X(7) contains many single nucleotide polymorphisms, including several mutations loca...

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Autors principals: Wickert, Lisa E., Blanchette, Joshua B., Waldschmidt, Noelle V., Bertics, Paul J., Denu, John M., Denlinger, Loren C., Lenertz, Lisa Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653848/
https://ncbi.nlm.nih.gov/pubmed/23691096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0063789
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