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The opposite effect of a 5-HT(1B) receptor agonist on 5-HT synthesis, as well as its resistant counterpart, in an animal model of depression

Flinders Sensitive Line (FSL) rat is as an animal model of depression with altered parameters of the serotonergic (5-HT) system function (5-HT synthesis rates, tissue concentrations, release, receptor density and affinity), as well as an altered sensitivity of these parameters to different 5-HT base...

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Main Authors: Skelin, Ivan, Kovačević, Tomislav, Sato, Hiroki, Diksic, Mirko
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653842/
https://ncbi.nlm.nih.gov/pubmed/22542420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2012.04.009
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