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A genetic rat model of depression, Flinders Sensitive Line, has a lower density of 5-HT(1A) receptors, but a higher density of 5-HT(1B) receptors, compared to control rats

Deficiencies in brain serotonergic neurotransmission, which is in part associated with the alteration of brain serotonin (5-HT) receptors, have been proposed as part of a neurochemical imbalance in affective disorders, including depression. The drugs used for the treatment of these disorders general...

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Hlavní autoři: Nishi, Kyoko, Kanemaru, Kazuya, Diksic, Mirko
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2656411/
https://ncbi.nlm.nih.gov/pubmed/19121358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2008.12.011
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