Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

The tumor microenvironment (TME) consists of cells, soluble factors, signaling molecules, extracellular matrix, and mechanical cues that can promote neoplastic transformation, support tumor growth and invasion, protect the tumor from host immunity, foster therapeutic resistance, and provide niches f...

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Autori principali: Swartz, Melody A., Iida, Noriho, Roberts, Edward W., Sangaletti, Sabina, Wong, Melissa H., Yull, Fiona E., Coussens, Lisa M., DeClerck, Yves A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653596/
https://ncbi.nlm.nih.gov/pubmed/22414581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-12-0122
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