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A novel chemical screening strategy in zebrafish identifies common pathways in embryogenesis and rhabdomyosarcoma development

The zebrafish is a powerful genetic model that has only recently been used to dissect developmental pathways involved in oncogenesis. We hypothesized that operative pathways during embryogenesis would also be used for oncogenesis. In an effort to define RAS target genes during embryogenesis, gene ex...

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Detalhes bibliográficos
Main Authors: Le, Xiuning, Pugach, Emily K., Hettmer, Simone, Storer, Narie Y., Liu, Jianing, Wills, Airon A., DiBiase, Antony, Chen, Eleanor Y., Ignatius, Myron S., Poss, Kenneth D., Wagers, Amy J., Langenau, David M., Zon, Leonard I.
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653557/
https://ncbi.nlm.nih.gov/pubmed/23615277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.088427
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