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A Coarse-Grained Protein Model in a Water-like Solvent

Simulations employing an explicit atom description of proteins in solvent can be computationally expensive. On the other hand, coarse-grained protein models in implicit solvent miss essential features of the hydrophobic effect, especially its temperature dependence, and have limited ability to captu...

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Detalhes bibliográficos
Main Authors: Sharma, Sumit, Kumar, Sanat K., Buldyrev, Sergey V., Debenedetti, Pablo G., Rossky, Peter J., Stanley, H. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653448/
https://ncbi.nlm.nih.gov/pubmed/23674146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep01841
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