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Interferon-induced revertants of ras-transformed cells: resistance to transformation by specific oncogenes and retransformation by 5-azacytidine.

Prolonged alpha/beta interferon (IFN-alpha/beta) treatment of NIH 3T3 cells transformed by a long terminal repeat-activated Ha-ras proto-oncogene resulted in revertants that maintained a nontransformed phenotype long after IFN treatment had been discontinued. Cloned persistent revertants (PRs) produ...

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Publicat a:Mol Cell Biol
Autors principals: Samid, D, Flessate, D M, Friedman, R M
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1987
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365343/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2439904/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.6.2196-2200.1987
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