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Notch signaling maintains Leydig progenitor cells in the mouse testis

During testis development, fetal Leydig cells increase their population from a pool of progenitor cells rather than from proliferation of a differentiated cell population. However, the mechanism that regulates Leydig stem cell self-renewal and differentiation is unknown. Here, we show that blocking...

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Detalhes bibliográficos
Main Authors: Tang, Hao, Brennan, Jennifer, Karl, Jeannie, Hamada, Yoshio, Raetzman, Lori, Capel, Blanche
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653410/
https://ncbi.nlm.nih.gov/pubmed/18927153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.024786
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