Amplification of the neu (c-erbB-2) oncogene in human mammmary tumors is relatively frequent and is often accompanied by amplification of the linked c-erbA oncogene.

We investigated alterations in the structure and expression of oncogenes in mammary tumors and mammary tumor-derived cell lines. In 16 of 95 samples, we detected amplification of the human neu oncogene, also known as c-erB-2, accompanied by overexpression in the tumors from which intact RNA could be...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	van de Vijver, M, van de Bersselaar, R, Devilee, P, Cornelisse, C, Peterse, J, Nusse, R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC365313/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3299059/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.7.5.2019-2023.1987
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